Anthem: Lucentis Payer Policy

Created by C. Denise Burrell, Modified on Wed, 8 Jan at 3:45 PM by C. Denise Burrell

Anthem: Lucentis Payer Policy (Beta Access)


HCPCS Code(s):
J2778
Precertification Required?Yes (Click Here for Full Policy)
Step Therapy Required? Yes (Click Here for Full Policy)
Provider Fax Form:✅ Available in SamaCare
FDA Approved Indications:
  • Diabetic macular edema (DME)
  • Diabetic retinopathy (with or without DME)
  • Neovascular (wet) age-related macular degeneration (AMD)
  • Macular edema following:
    • Branch retinal vein occlusion (BRVO)
    • Central retinal vein occlusion (CRVO)
  • Myopic choroidal neovascularization
  • Radiation retinopathy
Recommended Dosage:
  • DME and diabetic retinopathy:
    • 0.3 mg per eye – Each eye may be treated as frequently as every 4 weeks.
  • Other indications:
    • 0.5 mg per eye – Each eye may be treated as frequently as every 4 weeks.


Note:  Lucentis is subject to step therapy requirements as a non-preferred agent.Trial and failure, intolerance, or contraindication to a preferred agent are required before approval.
Preferred Agents include:
Avastin
Byooviz
Cimerli
Eylea


Other Pertinent Information

Lucentis is a non-preferred agent, and step therapy applies unless specified otherwise.


  • Quantity Limits:

    • DME and diabetic retinopathy: 0.3 mg per eye every 4 weeks
    • Other indications: 0.5 mg per eye every 4 weeks
  • Exclusion(s):
    • Indications not listed above are considered not medically necessary


Initial Approval Criteria

Authorization may be approved for 12 months when the following criteria are met:

  1. The member has a diagnosis of one of the following:
    • Diabetic macular edema (DME)
    • Diabetic retinopathy
    • Neovascular (wet) age-related macular degeneration
    • Macular edema following BRVO or CRVO
    • Myopic choroidal neovascularization
    • Radiation retinopathy


Continuation Criteria

Authorization may be approved for 12 months if:

  1. The member is currently receiving therapy with Lucentis.
  2. Documentation of positive clinical response is provided, such as improvement or maintenance of best corrected visual acuity (BCVA).

Sources:

https://www.anthem.com/ms/pharmacyinformation/VEGF.pdf

Additonal Resources

Medical Specialty Precertification Drug List: https://file.anthem.com/06347MUPENABS.pdf

Medical Step Therapy Drug List: https://file.anthem.com/A02605ANPENABS.pdf

Site of Care Drug List: https://file.anthem.com/06346MUPENABS.pdf


⚠️ Disclaimer: This article is a policy summary and does not guarantee coverage or approval. 

Policies may vary based on plan, payer-specific rules, state or regional requirements, benefit structure, formulary placement, and patient-specific considerations like diagnosis or clinical history. Always review the full policy and confirm details directly with the payer to ensure compliance. 


 

We're here to guide you through your prior authorization quest!





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