Anthem: Vabysmo Payer Policy

Created by C. Denise Burrell, Modified on Wed, 8 Jan at 3:44 PM by C. Denise Burrell

Anthem: Vabysmo Payer Policy (Beta Access)

TABLE OF CONTENTS


HCPCS Code(s):
J2777
Precertification Required?Yes (Click Here for Full Policy)
Step Therapy Required? Yes (Click Here for Full Policy)
Provider Fax Form:Generic Form ✅ Available in SamaCare
FDA Approved Indications:
  • Neovascular “wet” age-related macular degeneration (nAMD)
  • Diabetic macular edema (DME), including DME with diabetic retinopathy.
  • Macular edema following retinal vein occlusion (RVO).
Recommended Dosage:6 mg per eye
  • Each eye may be treated as frequently as every 4 weeks.


Note: 
1. Vabysmo may be used after failure or intolerance to a preferred agent.
2. Requests for intravitreal injections of Vabysmo may not be approved when criteria are unmet or for any other indication.


Other Pertinent Information

Vabysmo is a bispecific antibody targeting both VEGF-A and Angiopoietin-2 (Ang-2).

 

  • Quantity Limits:

    • 6 mg per eye; each eye may be treated as frequently as every 4 weeks

  • Exclusion(s):
    • All other indications not explicitly listed are considered not medically necessary 

Initial Approval Criteria

Authorization may be granted when the individual has a diagnosis of one of the following:

  1. Neovascular (wet) age-related macular degeneration (nAMD).
  2. Diabetic macular edema (DME), including with diabetic retinopathy.
  3. Macular edema following retinal vein occlusion (RVO).


Continuation Criteria

Authorization for 12 months may be granted if:

  1. The individual is currently receiving Vabysmo.
  2. Documentation of positive clinical response is provided.

Sources:

https://www.anthem.com/ms/pharmacyinformation/VEGF.pdf


⚠️ Disclaimer: This article is a policy summary and does not guarantee coverage or approval. 

Policies may vary based on plan, payer-specific rules, state or regional requirements, benefit structure, formulary placement, and patient-specific considerations like diagnosis or clinical history. Always review the full policy and confirm details directly with the payer to ensure compliance. 



We're here to guide you through your prior authorization quest!







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