Priority Health: Briumvi Payer Policy

Created by C. Denise Burrell, Modified on Mon, 24 Feb at 10:36 AM by C. Denise Burrell

Priority Health: Briumvi Payer Policy (Beta Access)

TABLE OF CONTENTS



MEDICAID

HCPCS Code(s):
J2329
Precertification Required?
Step Therapy Required?
 Not Specified  (Click Here for Full Policy)
Provider Fax Form:
Medicaid Medical Drug Request (✅ Available in SamaCare)
FDA Approved Indications:
Multiple Sclerosis
  • Primary Progressive Multiple Sclerosis (PPMS)

  • Relapsing-Remitting Multiple Sclerosis (RRMS)

Recommended Dosage:

Limited to FDA approved dose & frequency by diagnosis 

Approval Timeframe:
Initial Authorization: 2 years 
Continuation Authorization: 2 years


Prescriber Specialty Requirement:

  • The prescribing physician must be a Neurologist or a specialist in Multiple Sclerosis (MS).

Age Limitation:

  • Patients must be 18 years or older to qualify for Briumvi therapy.

Dose & Frequency:

  • Treatment must adhere to the FDA-approved dose and frequency based on the diagnosed MS subtype.


Initial Authorization Criteria:

  • Documentation is required to confirm a diagnosis of one of the following:

    • Primary Progressive Multiple Sclerosis (PPMS)

    • Relapsing-Remitting Multiple Sclerosis (RRMS)

    • Secondary Progressive Multiple Sclerosis (SPMS)



Additional Information:

  • Medical Policy Requirement:

    • Briumvi is subject to Priority Health’s Medical Policy 91414 - Infusion Services and Equipment.

    • Medications must be administered in an outpatient hospital infusion center.


Combination Therapy Restriction:

  • Briumvi will not be approved in combination with any other disease-modifying therapy for MS.


Continuation Criteria

  • Therapy may be discontinued if:

    • The patient is noncompliant with medical or pharmacologic therapy.

    • There is no demonstrable clinically significant improvement in the patient's condition after initiating Briumvi therapy.


Sources:

https://www.priorityhealth.com/-/media/DAAE5553F48C4FDBA84BABBAE764BB84.pdf



COMMERCIAL

HCPCS Code(s):J2329
Precertification Required?✅ Yes (Click Here For Full Policy)
Step Therapy Required?  Dependent (Click Here For Full Policy)
Provider Fax Form:Medical Drug Request (✅ Available in SamaCare)
FDA Approved Indications:Multiple Sclerosis
  • Primary Progressive Multiple Sclerosis (PPMS)

  • Relapsing-Remitting Multiple Sclerosis (RRMS)

Recommended Dosage:Not Specified
Note: Coverage is authorized for 24 months (2 years) 

Preferred Agents:

  • Ocrevus (ocrelizumab)
  • Ocrevus Zunovo (ocrelizumab/hyaluronidase)
  • Briumvi (ublituximab)

Eligibility Requirements:

To qualify for coverage, patients must meet the following criteria:

  • A definitive diagnosis of Primary Progressive Multiple Sclerosis (PPMS) confirmed by a neurologist or MS specialist.
  • A diagnosis of multiple sclerosis, including relapsing-remitting MS (RRMS) or secondary progressive MS, confirmed by a neurologist or MS specialist.


Additional Documentation Requirement:
  • Patients must submit documentation verifying a multiple sclerosis ICD-10 code (G35, G36.0, G37.0, G37.5) within the past 12 months for commercial individual members under Priority Health.



Continuation Criteria

  • Not Specified


Sources:

https://www.priorityhealth.com/-/media/81DACE8F00FF442799502209CC51780F.pdf

⚠️ Disclaimer: This article is a policy summary and does not guarantee coverage or approval. 

Policies may vary based on plan, payer-specific rules, state or regional requirements, benefit structure, formulary placement, and patient-specific considerations like diagnosis or clinical history. Always review the full policy and confirm details directly with the payer to ensure compliance. 


 

We're here to guide you through your prior authorization quest!


Was this article helpful?

That’s Great!

Thank you for your feedback

Sorry! We couldn't be helpful

Thank you for your feedback

Let us know how can we improve this article!

Select at least one of the reasons
CAPTCHA verification is required.

Feedback sent

We appreciate your effort and will try to fix the article